Understanding SSRIs
SSRIs, or Selective Serotonin Reuptake Inhibitors, are commonly prescribed antidepressants that work by increasing the levels of serotonin in the brain. However, SSRIs do not correct a chemical imbalance but rather work on a normal serotonin system, similar to how aspirin works on a normal prostaglandin system.
Effects on Fetal Development
Serotonin is essential for fetal development, particularly in brain development and other vital functions. SSRIs, by altering serotonin levels, can potentially affect these developmental processes.
Risks and Benefits
While SSRIs can be beneficial for some individuals, they are not universally effective. Moreover, SSRIs can cause emotional numbing and dependency, making it challenging for individuals to stop taking them without experiencing withdrawal symptoms.
Specific Risks
One of the possible risks associated with SSRIs during pregnancy is the potential for birth defects. There is also evidence suggesting that SSRIs can increase the risk of miscarriage and lower sperm count in males.
Postnatal Considerations
For women who have been on SSRIs during pregnancy, there is a potential risk of postnatal depression and challenges in bonding with their newborn. The emotional numbing caused by SSRIs can affect empathy and attachment.
Acetaminophen (Paracetamol) and Pregnancy
Acetaminophen, commonly known as paracetamol, is widely used during pregnancy for pain relief and fever reduction. Pro. Healy points out that paracetamol is not without its risks and its mechanism of action is not fully understood.
Potential Risks
Recent studies have suggested that children born to mothers who took paracetamol during pregnancy may have an increased risk of developing ADHD and autism spectrum disorders.
Epigenetic Effects
The effects of Paracetamol can influence gene expression and potentially lead to long-term developmental issues.
Alternatives
Healy emphasises the importance of a personalised approach to medication during pregnancy. Women should be encouraged to research and understand the options available to them. This includes considering non-pharmacological interventions such as cognitive-behavioral therapy (CBT) and other forms of psychotherapy.
